徐镇，研究员，博士生导师，鱼类黏膜免疫学科组组长。先后在山东农业大学（2002）、华中农业大学（2006、2009）获得农学学士、硕士和博士学位；2010年2月-2014年12月在美国宾夕法尼亚大学进行博士后研究，2015年1月-2021年2月，华中农业大学教授；2021年3月加入中国科学院水生生物研究所。主要从事鱼类黏膜免疫学的研究，以第一或通讯作者在Science Immunology、Nature Communications、PNAS、iScience、PLoS Pathogens、Journal of Immunology等国际杂志发表学术论文。先后主持国家自然科学基金、国家青年计划项目、国家重点研发计划“蓝色粮仓科技创新”课题和中国科学院引才计划项目等 

1. 鱼类黏膜免疫分子机制 

2. 鱼类黏膜疫苗与微生态制剂 

2021 

1. Xiaoting Zhang#, Yongyao Yu#, Haoyue Xu#, Zhenyu Huang, Xia Liu, Jiafeng Cao, Kaifeng Meng, Zhengbin Wu, Guangkun Han, Mengting Zhan, Liguo Ding, Weiguang Kong, Nan Li, Fumio Takizawa, Sunyer J Oriol, Zhen Xu*. Prevailing role of mucosal immunoglobulins and B cells in teleost skin immune responses to bacterial infection. Journal of Immunology. 2021, 206(3): 3054-3067. 

2020 

2. Zhen Xu#, Takizawa F#, Elisa C, Yasuhiro S, Yang D, Thomas J, Yongyao Yu, Irene Salinas*, Sunyer J O*. Mucosal immunoglobulins of primitive and modern vertebrates operate under the guidance of primordially conserved principles. Science Immunology. 2020, 10.1126/sciimmunol.aay3254.  

2019 

3. Yongyao Yu#, Weiguang Kong#, Haoyue Xu, Zhenyu Huang, Xiaoting Zhang, Liguo Ding, Shuai Dong, Guangmei Yin, Fen Dong, Wei Yu, Jiafeng Cao, Kaifeng Meng, Xia Liu, Yu Fu, Xuezhen Zhang, Yongan Zhang, Oriol Sunyer, Zhen Xu*. Convergent evolution of mucosal immune responses at the buccal cabity of teleost fish. iScience. 2019, 19: 821-835. 

4. Weiguang Kong#, Yongyao Yu#, Shuai Dong, Zhenyu Huang, Liguo Ding, Jiafeng Cao, Fen Dong, Xiaoting Zhang, Xia Liu, Haoyue Xu, Kaifeng Meng, Jianguo Su, Zhen Xu*. Pharyngeal immunity in early vertebrates provides functional and evolutionary insight into mucosal homeostasis. Journal of Immunology. 2019, 203(11): 3054-3067. 

2018 

5. Yongyao Yu#, Weiguang Kong#, Yaxing Yin, Fen Dong, Zhenyu Huang, Guangmei Yin, Shuai Dong, Irene Salinas, Yongan Zhang, Zhen Xu*. Mocosal immunoglobulins protect the olfactory organ of teleost fish against parastic infection. PLoS Pathogens. 2018, 14(11):e1007251. 

2016及以前 

6. Zhen Xu, Takizawa F, Parra D, Gomez D, Jorgensen G L, LaPatra S E, Sunyer J O. Mucosal immunoglobulins at respiratory surfaces mark an ancient association that predates the emergence of tetrapods. Nature Communitions. 2016, 7:10728.  

7. Zhen Xu#, Parra D#, Gomez D#, Salinas I, Zhang Y A, Jorgensen G L, Skjodt K, Rasmussen K J, Buchmann K, LaPatra S E, Sunyer J O. Teleost skin, an ancient mucosal surface that solicits gut-like immune response. PNAS. 2013, 35: 1729-1739.